Housed in Panagiotideio Mansion, a neoclassical building of the City donating the Archaeological Service.

The collection of eskainiastike in 1989  includes artifacts from prehistoric to early Christian years in various positions of the Kozani prefecture.
The most important exhibits are:

Bronze pendant from Apidea, 7th century BC

Inscribed silver flask from Kozani, beginning fifth century BC

Twin golden buckle from a tomb of the 4th century BC from Apidea.

Bronze vases from the tomb of the 4th century BC from Apidea.

Gold earring of 4th century BC Necropolis of Kozani.

Grave offerings from the Necropolis of Kozani.

Inscription in a letter of Philip V of Kozani Valley.

Marble statue from Mesovaio child, Roman epoch.

Female head marble statue of Elani, 4th century BC

Gold earrings Ano Komi, second half of 4th century BC